Difolin

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Difolin

Dichlorophen

Dichlorophen is reported as an ingredient of Difolin in the following countries:

• United States

Toluene

Toluene is reported as an ingredient of Difolin in the following countries:

• United States

International Drug Name Search

Sirolimus

In the US, Sirolimus (sirolimus systemic) is a member of the drug class selective immunosuppressants and is used to treat Organ Transplant, Rejection Prophylaxis.

US matches:

• Sirolimus


• Sirolimus Solution

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L04AA10

CAS registry number (Chemical Abstracts Service)

0053123-88-9

Chemical Formula

C51-H79-N-O13

Molecular Weight

914

Therapeutic Category

Selective immunosuppressant

Chemical Names

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dime (WHO)

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-10,2 (IUPAC)

Rapamycin (USAN)

Foreign Names

• Sirolimusum (Latin)
• Sirolimus (German)
• Sirolimus (French)
• Sirolimus (Spanish)

Generic Names

• Sirolimus (OS: BAN, USAN, DCF)
• AY-22989 (IS: Wyeth)
• NSC-226080 (IS)
• NSC-606698 (IS)
• Rapamune (IS)
• Rapamycin (IS)
• WY-090217 (IS: Wyeth)

Brand Names

• Rapamune
  Pfizer, Switzerland; PharmaSwiss, Croatia (Hrvatska); Wyeth, Argentina; Wyeth, Austria; Wyeth, Australia; Wyeth, Belgium; Wyeth, Brazil; Wyeth, Canada; Wyeth, Chile; Wyeth, China; Wyeth, Colombia; Wyeth, Costa Rica; Wyeth, Czech Republic; Wyeth, Germany; Wyeth, Denmark; Wyeth, Spain; Wyeth, Finland; Wyeth, France; Wyeth, Greece; Wyeth, Guatemala; Wyeth, Hong Kong; Wyeth, Honduras; Wyeth, Hungary; Wyeth, Ireland; Wyeth, Israel; Wyeth, India; Wyeth, Iceland; Wyeth, Italy; Wyeth, Luxembourg; Wyeth, Mexico; Wyeth, Malaysia; Wyeth, Nicaragua; Wyeth, Netherlands; Wyeth, Norway; Wyeth, New Zealand; Wyeth, Oman; Wyeth, Panama; Wyeth, Philippines; Wyeth, Portugal; Wyeth, Romania; Wyeth, Serbia; Wyeth, Sweden; Wyeth, Singapore; Wyeth, Slovenia; Wyeth, Slovakia; Wyeth, El Salvador; Wyeth, Thailand; Wyeth, Turkey; Wyeth, Taiwan; Wyeth, United States; Wyeth, Venezuela; Wyeth, South Africa; Wyeth Pharmaceuticals, United Kingdom



• Torisel
  Wyeth, Belgium



• Yixinke
  NCPC GeneTech, China

International Drug Name Search

Glossary

BAN	British Approved Name
DCF	Dénomination Commune Française
IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Detrol

Pronunciation: tol-TER-oh-deen
Generic Name: Tolterodine
Brand Name: Detrol

Detrol is used for:

Treating overactive bladder with symptoms of urinary frequency, urgency, and leakage. It may also be used for other conditions as determined by your doctor.

Detrol is an antimuscarinic (anticholinergic) agent. It works by blocking a chemical that causes contractions of the bladder.

Do NOT use Detrol if:

• you are allergic to any ingredient in Detrol or to fesoterodine


• you have uncontrolled narrow-angle glaucoma, trouble urinating, or have slowed emptying of your stomach


• you are taking a solid oral potassium product (eg, tablet)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Detrol:

Some medical conditions may interact with Detrol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have glaucoma; a blockage of the bladder, stomach, or bowel; stomach or bowel problems (eg, slowed moving of the bowel, constipation); spinal cord injury; dementia; liver or kidney problems; or myasthenia gravis (muscle weakness)


• if you or a family member have a history of irregular heartbeat (eg, prolonged QT, long QT syndrome)

Some MEDICINES MAY INTERACT with Detrol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiarrhythmics (eg, amiodarone, quinidine) because the risk of irregular heartbeat may be increased


• Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by Detrol


• Other anticholinergics (eg, scopolamine), azole antifungals (eg, itraconazole, ketoconazole, miconazole), cyclosporine, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin, erythromycin), nefazodone, or vinblastine because they may increase the risk of Detrol's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Detrol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Detrol:

Use Detrol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Detrol. Talk to your pharmacist if you have questions about this information.


• Take Detrol by mouth with or without food.


• Detrol works best if it is taken at the same time each day.


• If you miss a dose of Detrol, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Detrol.

Important safety information:

• Detrol may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Detrol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do NOT change your dose of Detrol without checking with your doctor.


• Detrol should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• Caution is advised when using Detrol in CHILDREN; they may be more sensitive to its effects, especially an increased risk of urinary tract infection or behavior or attention problems.


• PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Detrol while you are pregnant. It is not known if Detrol is found in breast milk. Do not breast-feed while taking Detrol.

Possible side effects of Detrol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; dizziness; drowsiness; dry eyes; dry mouth; headache; indigestion; stomach pain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); chest pain; confusion; difficult or painful urination; disorientation; fainting; fast or irregular heartbeat; hallucinations; memory problems; severe dizziness; swelling of the hands, ankles, or feet.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Detrol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; difficulty urinating; dilated pupils; dry mouth; excitation; fast heartbeat; hallucinations; seizures.

Proper storage of Detrol:

Store Detrol at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Detrol out of the reach of children and away from pets.

General information:

• If you have any questions about Detrol, please talk with your doctor, pharmacist, or other health care provider.


• Detrol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Detrol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Detrol resources

• Detrol Side Effects (in more detail)
• Detrol Dosage
• Detrol Use in Pregnancy & Breastfeeding
• Drug Images
• Detrol Drug Interactions
• Detrol Support Group
• 8 Reviews for Detrol - Add your own review/rating

• Detrol Prescribing Information (FDA)


• Detrol Consumer Overview


• Detrol Monograph (AHFS DI)


• Detrol Advanced Consumer (Micromedex) - Includes Dosage Information


• Detrol LA Prescribing Information (FDA)

Compare Detrol with other medications

• Overactive Bladder
• Urinary Incontinence

Docmetoclo

Docmetoclo may be available in the countries listed below.

Ingredient matches for Docmetoclo

Metoclopramide

Metoclopramide hydrochloride (a derivative of Metoclopramide) is reported as an ingredient of Docmetoclo in the following countries:

• Belgium

International Drug Name Search

Apyrene

Apyrene may be available in the countries listed below.

Ingredient matches for Apyrene

Paracetamol

Paracetamol is reported as an ingredient of Apyrene in the following countries:

• Venezuela

International Drug Name Search

Amidophen

Amidophen may be available in the countries listed below.

Ingredient matches for Amidophen

Aminophenazone

Aminophenazone is reported as an ingredient of Amidophen in the following countries:

• Bulgaria

International Drug Name Search

Hepsal

Hepsal may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

UK matches:

• Hepsal injection 10 iu/ml (SPC)

Ingredient matches for Hepsal

Heparin

Heparin sodium salt (a derivative of Heparin) is reported as an ingredient of Hepsal in the following countries:

• Greece


• Ireland


• Malta


• United Kingdom

International Drug Name Search

Glossary

SPC	Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.