Thursday 8 October 2009

Sirolimus




In the US, Sirolimus (sirolimus systemic) is a member of the drug class selective immunosuppressants and is used to treat Organ Transplant, Rejection Prophylaxis.

US matches:

  • Sirolimus

  • Sirolimus Solution

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L04AA10

CAS registry number (Chemical Abstracts Service)

0053123-88-9

Chemical Formula

C51-H79-N-O13

Molecular Weight

914

Therapeutic Category

Selective immunosuppressant

Chemical Names

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dime (WHO)

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-10,2 (IUPAC)

Rapamycin (USAN)

Foreign Names

  • Sirolimusum (Latin)
  • Sirolimus (German)
  • Sirolimus (French)
  • Sirolimus (Spanish)

Generic Names

  • Sirolimus (OS: BAN, USAN, DCF)
  • AY-22989 (IS: Wyeth)
  • NSC-226080 (IS)
  • NSC-606698 (IS)
  • Rapamune (IS)
  • Rapamycin (IS)
  • WY-090217 (IS: Wyeth)

Brand Names

  • Rapamune
    Pfizer, Switzerland; PharmaSwiss, Croatia (Hrvatska); Wyeth, Argentina; Wyeth, Austria; Wyeth, Australia; Wyeth, Belgium; Wyeth, Brazil; Wyeth, Canada; Wyeth, Chile; Wyeth, China; Wyeth, Colombia; Wyeth, Costa Rica; Wyeth, Czech Republic; Wyeth, Germany; Wyeth, Denmark; Wyeth, Spain; Wyeth, Finland; Wyeth, France; Wyeth, Greece; Wyeth, Guatemala; Wyeth, Hong Kong; Wyeth, Honduras; Wyeth, Hungary; Wyeth, Ireland; Wyeth, Israel; Wyeth, India; Wyeth, Iceland; Wyeth, Italy; Wyeth, Luxembourg; Wyeth, Mexico; Wyeth, Malaysia; Wyeth, Nicaragua; Wyeth, Netherlands; Wyeth, Norway; Wyeth, New Zealand; Wyeth, Oman; Wyeth, Panama; Wyeth, Philippines; Wyeth, Portugal; Wyeth, Romania; Wyeth, Serbia; Wyeth, Sweden; Wyeth, Singapore; Wyeth, Slovenia; Wyeth, Slovakia; Wyeth, El Salvador; Wyeth, Thailand; Wyeth, Turkey; Wyeth, Taiwan; Wyeth, United States; Wyeth, Venezuela; Wyeth, South Africa; Wyeth Pharmaceuticals, United Kingdom


  • Torisel
    Wyeth, Belgium


  • Yixinke
    NCPC GeneTech, China

International Drug Name Search

Glossary

BANBritish Approved Name
DCFDénomination Commune Française
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

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