Read PLR Article Directory Uganda: colistin, neomycin, thonzonium, and hydrocortisone Otic

koe-LIS-tin SUL-fate, nee-oh-MYE-sin SUL-fate, hye-droe-KOR-ti-sone AS-e-tate, thon-ZOE-nee-um BROE-mide

Commonly used brand name(s)

In the U.S.

Coly-Mycin S

Cortisporin TC

In Canada

Coly-Mycin

Available Dosage Forms:

Suspension

Therapeutic Class: Anti-Infective/Anti-Inflammatory Combination

Pharmacologic Class: Hydrocortisone

Chemical Class: Neomycin

Uses For colistin, neomycin, thonzonium, and hydrocortisone

Colistin, neomycin, and hydrocortisone combination contains two antibiotics and a cortisone-like medicine. It is used in the ear to treat infections of the ear canal and to help provide relief from redness, irritation, and discomfort of certain ear problems.

Colistin, neomycin, and hydrocortisone combination is available only with your doctor's prescription.

Before Using colistin, neomycin, thonzonium, and hydrocortisone

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For colistin, neomycin, thonzonium, and hydrocortisone, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to colistin, neomycin, thonzonium, and hydrocortisone or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of colistin, neomycin, and hydrocortisone combination in children with use in other age groups, colistin, neomycin, thonzonium, and hydrocortisone is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of colistin, neomycin, and hydrocortisone combination in the elderly with use in other age groups, colistin, neomycin, thonzonium, and hydrocortisone is not expected to cause different side effects or problems in older people than it does in younger adults.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking colistin, neomycin, thonzonium, and hydrocortisone, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using colistin, neomycin, thonzonium, and hydrocortisone with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

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Using colistin, neomycin, thonzonium, and hydrocortisone with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alcuronium

Aldesleukin

Atracurium

Bupropion

Cidofovir

Cisatracurium

Colistimethate Sodium

Decamethonium

Doxacurium

Ethacrynic Acid

Fazadinium

Furosemide

Gallamine

Hexafluorenium

Metocurine

Mivacurium

Pancuronium

Pipecuronium

Quetiapine

Rapacuronium

Rocuronium

Sorafenib

Tacrolimus

Tubocurarine

Vecuronium

Using colistin, neomycin, thonzonium, and hydrocortisone with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alatrofloxacin

Alcuronium

Atracurium

Balofloxacin

Bumetanide

Cinoxacin

Ciprofloxacin

Clinafloxacin

Colestipol

Enoxacin

Fleroxacin

Flumequine

Gallamine

Gemifloxacin

Grepafloxacin

Hexafluorenium

Itraconazole

Levofloxacin

Licorice

Lomefloxacin

Metocurine

Moxifloxacin

Norfloxacin

Ofloxacin

Pefloxacin

Primidone

Prulifloxacin

Rifapentine

Rosoxacin

Rufloxacin

Saiboku-To

Sparfloxacin

Temafloxacin

Tosufloxacin

Trovafloxacin Mesylate

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of colistin, neomycin, thonzonium, and hydrocortisone

Before applying colistin, neomycin, thonzonium, and hydrocortisone, thoroughly clean the ear canal and dry it with a sterile cotton applicator.

You may warm the ear drops to body temperature (37 °C or 98.6 °F), but no higher, by holding the bottle in your hand for a few minutes before applying. If colistin, neomycin, thonzonium, and hydrocortisone gets too warm, it may break down and not work properly.

To apply colistin, neomycin, thonzonium, and hydrocortisone:

Lie down or tilt the head so that the infected ear faces up. Gently pull the earlobe up and back for adults (down and back for children) to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for about 5 minutes to allow the medicine to coat the ear canal. (For young children and other patients who cannot stay still for 5 minutes, try to keep the ear facing up for at least 1 or 2 minutes.) Your doctor may have inserted a gauze or cotton wick into your ear and may want you to keep the wick moistened with colistin, neomycin, thonzonium, and hydrocortisone. Your doctor also may have other directions for you, such as how long you should keep the wick in your ear or when you should return to your doctor to have the wick replaced. If you have any questions about this, check with your doctor.

To keep the medicine as germ-free as possible, do not touch the dropper to any surface (including the ear). Also, keep the container tightly closed.

Do not use colistin, neomycin, thonzonium, and hydrocortisone for more than 10 days unless otherwise directed by your doctor.

To help clear up your infection completely, keep using colistin, neomycin, thonzonium, and hydrocortisone for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using colistin, neomycin, thonzonium, and hydrocortisone too soon, your symptoms may return. Do not miss any doses.

Dosing

The dose of colistin, neomycin, thonzonium, and hydrocortisone will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of colistin, neomycin, thonzonium, and hydrocortisone. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For otic suspension (ear drops) dosage form:
- For infections of the ear canal:
  - Adults—Use four drops in the ear every six to eight hours.
  - Children—Use up to three drops in the ear every six to eight hours.

Missed Dose

If you miss a dose of colistin, neomycin, thonzonium, and hydrocortisone, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using colistin, neomycin, thonzonium, and hydrocortisone

If your symptoms do not improve within 1 week, or if they become worse, check with your doctor immediately.

colistin, neomycin, thonzonium, and hydrocortisone Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Itching, skin rash, redness, swelling, or other sign of irritation not present before use of colistin, neomycin, thonzonium, and hydrocortisone

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More colistin, neomycin, thonzonium, and hydrocortisone Otic resources

Colistin, neomycin, thonzonium, and hydrocortisone Otic Use in Pregnancy & Breastfeeding
Colistin, neomycin, thonzonium, and hydrocortisone Otic Drug Interactions
Colistin, neomycin, thonzonium, and hydrocortisone Otic Support Group
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Thursday 6 September 2012

colistin, neomycin, thonzonium, and hydrocortisone Otic